We all need to be aware that we’re at an increased risk of becoming a diabetic.
Even though we’ve talked about this in the past, it always helps to discuss all of the health problems associated with severe psoriasis.
Ambulatory Monitoring Shows Persistent HTN Common After Severe Preeclampsia CDC: Pediatric Asthma Control Improving in U.S. Earn Free CME Credits by reading the latest medical news in your specialty. Patients with psoriasis covering more than 10% of their body surface area (BSA) were at significantly greater risk of developing type 2 diabetes (T2DM) over approximately 4 years compared with those without psoriasis, according to a large, prospective, population-based cohort study.
After adjusting for age, sex, and body mass index (BMI), the investigators found that patients with greater than 10% skin involvement were 64% more likely to develop T2DM at a hazard ratio (HR) of 1.64 (95% Confidence Interval (CI,1.23-2.18) compared with patients without psoriasis (P=0.004), reported Marilyn Wan, MBChB, MPH, of the University of Pennsylvania Perelman School of Medicine in Philadelphia, and colleagues, writing online in the Journal of the American Academy of Dermatology.
Furthermore, the risk of developing T2DM over the same follow-up interval was approximately 20% higher for each 10% increase in BSA affected by the disease. This suggests that there is a dose-response relationship between the risk of developing T2DM and the degree of skin involvement among patients with psoriasis, the investigators said.
“We estimate, on the basis of our data, that patients with psoriasis affecting 10% or more of their BSA have about a 60% higher risk per year for development of T2DM, which translates into an extra 25,000 new cases of diabetes annually worldwide that are attributable to severe psoriasis.
thumbnail courtesy of medpagetoday.com
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Additional reading: Psoriasis Cream That Works – 3 Best OTC Psoriasis Treatments